The KineOmics Lab studies how physical activity, exercise, and related lifestyle exposures become biologically embedded to influence health and disease. We integrate multi-omic data, with a focus on DNA methylation, from population-based epidemiologic studies and intervention studies to identify molecular signatures associated with movement and its health effects.

A major focus of the lab is developing epigenetic biomarkers that enable molecular phenotyping of complex exposures and health outcomes. This includes DNA methylation-based biomarkers of physical activity that capture long-term behavioral patterns. We also investigate how social and environmental contexts shape, and interact with, lifestyle and behavioral exposures to influence biological pathways related to aging, cardiometabolic health, and chronic disease.

Overall, our work aims to improve how behavioral exposures are measured and understood at the molecular level, bridging physical activity research, molecular epidemiology, and population health.