“The Integrative Molecular Genetics Laboratory aims to understand telomere biology in stem cells, aging, and cancer. Our research focuses on how telomeres (the protective caps at the end of each DNA strand) and telomerase (an enzyme that maintains and lengthens telomeres) are regulated and how they become dysfunctional in aging and cancer. By understanding telomere biology, we hope to develop exercise and diet interventions and drug and small molecule therapies to manipulate telomere biology in aging and cancer.”
—Dr. Andy Ludlow, Director and Assistant Professor of Movement Science
Funded Ph.D. position at U-M Kinesiology. The Integrative Molecular Genetics Laboratory is seeking a graduate student that is highly motivated to purse doctoral work focusing on telomere biology in aging, cancer, and how it is impacted by exercise. Currently the laboratory is funded by a National Cancer Institute Pathway to Independence award (K99/R00). Our research agenda includes understanding the basic mechanisms of how cells utilize hTERT and telomerase to survive, with the ultimate goal of one day learning to either shorten telomeres for cancer therapies or elongate telomeres in regenerative medicine approaches.