Greg Cartee

The research in the Muscle Biology Laboratory is focused on skeletal muscle metabolism. We are especially interested in the modulation of glucose transport by exercise and calorie restriction (consuming 60% of ad libitum uptake), and how these interventions are influenced by advancing age. Each of these interventions can lead to a substantial improvement in skeletal muscle insulin sensitivity, which is a significant benefit for health. The improved insulin sensitivity after a bout of exercise facilitates the restoration of muscle glycogen stores, thereby improving the capacity for subsequent exercise. Our long-term goal is to understand the specific mechanisms whereby these physiological interventions lead to improved insulin sensitivity.