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Substrate Metabolism Laboratory

Understanding how exercise and diet improve metabolic health
A close-up of adipose (fat) tissue
About

The Substrate Metabolism Laboratory conducts research centered around exercise and diet, attempting to discover how these factors affect the risk and prevalence of metabolic diseases such as Type 2 diabetes. The health benefits for exercising are well known, but what is still unclear are the actual mechanisms of  exercise and diet that produce healthier  lives. By studying and understanding these mechanisms, we will be able to target specific training programs or medications designed to reduce the risk of disease.


SML Studies

We currently are recruiting subjects for the following research study projects.  

  • Weight Loss (WAX) Research Study
  • Weight Management (LG) Research Study

If interested in participating in any of the above studies, please complete the General Pre-screening Questionnaire at myumi.ch/51VM2 to determine your eligibility to continue screening for our studies.  If eligible, our study coordinator will contact you via email to set up a screening appointment.

 


Director(s)

Jeffrey Horowitz, PhD

[email protected]
Download CV Michigan Research Expert Profile

Member(s)

Staff

Suzette Howton, RDN

,
[email protected]

Thomas Rode, MS

,
[email protected]
PhD Student(s)

Tao Zhang

,
[email protected]

Post-Doctoral Fellow

  • Hayley Billingsley, PhD ([email protected])

Master's Student(s)

  • Sanjay Dronavalli, MD
  • Ina Gjoka

Undergraduate Student(s)

  • Olivia Katherine Chugh
  • Sierra Ellis
  • Sophia Ghayur
  • Shriya Mehta
  • Ryan Alexander Salzman
  • Gayoung Yang

Collaborator(s)

Charles Burant, MD, PhD - Dr Robert C and Veronica Atkins Professor of Metabolism, Professor of Internal Medicine, Professor of Molecular and Integrative Physiology, Director of the A Alfred Taubman Medical Research Institute at Michigan Medicine, Medical School and Professor of Nutritional Sciences, School of Public Health

Greg Cartee, PhD - Associate Dean for Research, Professor of Kinesiology, School of Kinesiology, Research Professor, Institute of Gerontology and Professor of Molecular and Integrative Physiology, Medical School

Jacob Matthew Haus, PhD - Associate Professor of Kinesiology

Scott Hummel, MD - Associate Professor of Internal Medicine, Medical School

Stephen CJ Parker, PhD - Associate Professor of Computational Medicine and Bioinformatics and Associate Professor of Human Genetics, Medical School

Projects

Weight Loss (WAX) Research Study
Weight Management (LG) Research Study
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News

Making science make sense
Movement science professor Jeff Horowitz explains how he tries to translate his research for the public and why he’s passing those methods down to the next generation.
November 4, 2025
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