MVS professor Jeff Horowitz, director of the Substrate Metabolism Laboratory, received grants for nearly $3 million from the National Institutes of Health (NIH) and $600,000 from the American Diabetes Association (ADA).
The NIH award is for a 5-year study to examine the effects of high intensity interval training (HIIT) on metabolic health in obesity. HIIT has become an increasingly popular alternative to “conventional” exercise training, and although it has been confirmed to be a safe form of exercise--even in obese patients--little is known about how HIIT can improve health. This project will comprehensively examine adaptations to HIIT at the whole-body, tissue, and cellular levels.
The 3-year grant for $600,000 from the the American Diabetes Association (ADA) will allow Dr. Horowitz and his lab to focus on how alterations in the structure and metabolic function of fat tissue may underlie the development of metabolic diseases in obesity. Identifying novel factors that may result in the development of chronic disease could lead to targeted strategies for the prevention and treatment of obesity-related diseases.